99.5% Purity Female Steroids Formestane / Lentaron For Anti Breast
Cancer Without Side Effect CAS 566-48-3
1 . Basic View :
Product name: Formestane
Other name: Lentaron;FORMESTAQNE;hydroxyandrostenedione
CAS Registry Number: 566-48-3
Molecular Formula: C19H26O3
Molecular Weight: 302.41
Appearance: White crystalline powder
Usage:An antitumor drug. An aromatase inhibitor
2 . Brief Introduction :
Formestane (Lentaron) is used for natural or artificial
postmenopausal breast cancer patients, including tamoxifen and
other endocrine treatment of patients is invalid
Formestane (Lentaron) is a type steroidal aromatase inhibitor. It
is used in the treatment of estrogen-receptor positive breast
cancer in postmenopausal women. It is available as an intramuscular
Formestane is often used to suppress estrogen production from
anabolic steroids or prohormones. It also acts as a prohormone to
4-hydroxytestosterone, an active steroid which displays weak
androgenic activity in addition to acting as a mild aromatase
3 . How it works :
Formestane is a second generation, irreversible, steroidal
aromatase inhibitor. It inhibits the aromatase enzyme responsible
for converting androgens to estrogens, thereby preventing estrogen
production. Breast cancer may be estrogen sensitive or insensitive.
A majority of breast cancers are estrogen sensitive. Estrogen
sensitive breast cancer cells depend on estrogen for viability.
Thus removal of estrogen from the body can be an effective
treatment for hormone sensitive breast cancers. Formestane has been
targeted specifically for the treatment of postmenopausal women.
Unlike premenopausal women who produce most estrogen in the
ovaries, postmenopausal women produce most estrogen in peripheral
tissues with the help of the aromatase enzyme. Formestane, an
aromatase inhibitor, can thus help to decrease the local production
of estrogen by blocking the aromatase enzyme in peripheral tissues
(ie. Adispose tissue of the breast) to treat hormone sensitive
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